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Autism

Defeat Autism Now (DAN) Conferences

The 12th DAN Conference was  held October 3-5, 2003, in Portland, Oregon, at the downtown Marriott. The conference featured presentations by the nation's leading experts on research and treatment of autism, as well as by parents of autistic children. A central theme of the conference was practical advice for parents on the treatment and management of autistic children. 

The 13th Conference was held in Los Angeles on October 1-3, 2004. A highlight of the conference was the introduction of a group of recovered autistic children. In reporting on the conference, Dr. Bernard Rimland said "The evidence is overwhelming, and continues to grow, that thimerosal-containing vaccines are a major cause of the world-wide autism epidemic." His statement is a direct contradiction to a story in the January, 2005 Discover magazine entitled "Childhood vaccines' link to autism is debunked." The story cites several studies in which no significant link between the vaccines and autism were found. It doesn't appear that an end to this controversy is in sight. However, according to the Discover article, as a precaution thimerosal has been replaced in most vaccines, except for a flu vaccine manufactured by Aventis.

Autism Advice From The American Academy Of Pediatrics

The May, 2002, issue of the American Academy of Pediatrics' journal contains guidelines for recognizing and managing autism. The guidelines contain a clear position on the controversial link between the measles, mumps, and rubella vaccination and autism: namely, that there is no scientific evidence for the alleged link. Thus physicians should, according to the guidelines, continue to encourage the vaccination for all children.

Beyond that, the guidelines emphasize early detection of autism through careful observation and concentrated attention to the concerns of parents about their children's development. Such early detection, combined with "early, appropriate, and consistent intervention," is said to produce better long-term outcomes for children with autistic spectrum disorders.

Autism: more common, but more clues for earlier treatment

A British study reported out of Cambridge University by Dr. Fiona Scott of the Autism Research Centre there indicated that 58 of 10,000 children were diagnosable with autism. Previous estimates were about 5 in 10,000, less than 1/11 the new estimate. Either there is an epidemic of autism, at least in Cambridgeshire where the study was done, or the criteria for what constitutes autism have undergone radical revision. In the Cambridge study, only children who had a definite clinical diagnosis were counted, so the rates were not inflated by a lax application of existing criteria.

The root cause of autism remains a mystery, but two chemically identifiable differences between normal and autistic children have been reported. The first, reported at the May meeting of the American Psychiatric Association in New Orleans, is that the ratio of copper to zinc is higher in autistic than in normal children. Dr. William Walsh of the Pfeiffer Center in Chicago believes that the reason for the discrepancy is that a protein, metallothionein, that plays a role in the metabolism of metals, does not function properly in autistic people. The hypothesis that zinc is deficient in some autistics is not new; some autistics are already given zinc therapy, but Dr. Walsh thinks that the metallothionein problem could be a root cause of autism.

Another study recently reported in Annals of Neurology with Dr. Karin Nelson of the United States' National Institute of Neurological Disorders and Stroke as lead author showed that neonatal blood samples of children who later became autistic contained abnormally high concentrations of neural growth factors. The high concentration was also observed in children who later were mentally retarded. The exact significance of the elevated levels is unknown, but detection of the abnormal level of neural growth factor makes early intervention and planning possible.

Autism not Related to Inoculations?

In the February, 2001 issue of the journal, Pediatrics, Dr. Eric Fombonne published a letter arguing that the sharp rise in cases of autism is largely illusory. He points out that increasing population and changes in diagnostic accuracy may contribute to the apparent rise in the number of cases. Other researchers also question the association between MMR vaccine and autism. However, there does not seem to be any alternative explanation yet for the great relative increase in the number of cases of late-onset autism compared to early-onset autism; the late-onset cases appear to occur at about the time the vaccine is typically administered.   

Controversy About Autism-Vaccine Link Continues

In the latest issue of Autism Research Review (Volume 15, No. 2) Dr. Bernard Rimland says "Has the autism/MMR link been disproved? Absolutely not." Dr. Rimland is arguably the world's leading expert on autism, the father of an autistic adult, the author of a prize-winning book on autism, and a student of the disorder for about 40 years. He believes that the media have misled the public about the Institute of Medicine's (IOM's) allegedly negative conclusion about the link. He quotes from the IOM report, ". . . the committee recommends that this issue receive continued attention. . . its conclusion does not exclude the possibility that MMR vaccine could contribute to ASD in a small number of children."

Dr. Rimland says "Thousands of U.S. and U.K. families say--and can demonstrate with videotapes and photos--that their children were normal prior to being vaccinated, reacted badly to the vaccination, and became autistic shortly after."

We cannot, of course, be certain that some other factor did not cause the autism; thus, as the saying goes, "the beat goes on," and parents must wait a little longer for a stronger consensus on this matter to develop. Meanwhile, those who want advice on vaccinations from the Autism Research Institute can get it by sending a self-addressed, stamped business size (#10) envelope marked "vaccine advice" to ARI, 4182 Adams Avenue, San Diego, CA (USA), 92116.  

Autism Debate Goes on, and on, and on . . .

          In the latest issue of Autism Research Review International Dr. Bernard Rimland once again suggests that autism is linked to unsafe levels of mercury by unsafe immunizations. Specifically, the mercury-laden preservative thimerosal, used to make it possible to store multiple doses of vaccine in a single container, is identified as the culprit. Dr. Rimland cites an admission by Neal Halsey, M.D., of Johns Hopkins University, that he and others had failed to recognize that children were receiving potentially toxic amounts of mercury in vaccinations. A subsequent meeting of the Institute of Medicine resulted in a recommendation that physicians should not administer vaccines containing thimerosal unless no thimerosal-free vaccine is available. Given this recommendation, parents might be wise to ask physicians whether any vaccine they propose to administer contains thimerosal, and decide what to do after hearing the answer.

Autistic Boy Analyzes His Own Condition

          On the front page of the San Diego Union-Tribune of November 19, 2002, Sandra Blakeslee of the New York Times News Service reports on the unique talent of an autistic boy. Tito Mukhopadhyay, a 14-year-old from India, reads well and writes fluently, although he has the typical hand-flapping and twirling symptoms associated with autism. With respect to these symptoms, he says "I am calming myself. My senses are so disconnected, I lose my body. So I flap. If I don't do this, I feel scattered and anxious." Tito's feeling of losing his body is probably characteristic of autistic people, who seem to have little sense of their bodies. Tito's articulation is poor; autistic people often have difficulty with motor behavior and appear clumsy, but Tito is able to write clearly.

          Laboratory tests reveal that Tito cannot detect lights that go on within fewer than 3 seconds after a sound is presented; this is a dramatic demonstration of the autistic tendency to focus on only one sense at a time. Tito also says that vision is painful, and that he chooses to focus on audition as his primary sensory modality.

          Tito's mother taught him at home, day and night, and refused to let him withdraw from the world. She used food rewards to encourage him to learn the alphabet and to read; food seems to be an unusually effective reward for autistic children. He reads widely, remembers what he reads, and reports accurately on what he remembers. 

Secretin No Cure for Autism

          A careful new double-blind study published in the November, 2002 edition of the Journal of the American Academy of Child Adolescent Psychiatry revealed no greater effect of a single injection of secretin than of a single placebo injection. Both natural and synthetic forms of secretin were tested at centers in Colorado and Washington. Although placebos may themselves produce a significant effect, this study indicates that the money spent on secretin is probably wasted. Multiple injections might produce an effect, but that has not been demonstrated.

          What is needed, according to Geraldine Dawson, who co-directed the study, is more research to determine the causes of autism. Meanwhile, parents would be well advised to use techniques that are proven to be effective, like behavioral interventions or medications that are shown to be effective against some of the symptoms of autism

 

 

 

                                                                                                                                Last updated  12/17/04

 
     
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