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Dementia Caused by HIV Infection The dementia that may result from HIV infection is caused by brain deterioration associated with the breakdown of the immune system. Brain white matter is destroyed in multiple locations. Behaviorally, the symptoms are not unlike those seen in other dementias; they typically include forgetfulness, lack of ability to concentrate or solve problems, slowness, apathy, and social withdrawal. Multiple deficiencies in motor movements and motor control are also typical. Children, as well as adults, are susceptible to HIV dementia. Secondary infections and tumors may contribute to the development of HIV dementia. So may the side effects of drugs used to combat HIV. There is no cure for HIV dementia, but the onset of full-blown AIDS, and thus of dementia, can be greatly delayed by medications already available or under development. If the dementia is the result of a treatable tumor or secondary infection, there is hope of reversing it, at least temporarily; even dementia that is a direct result of HIV may be improved somewhat by anti-HIV drugs like AZT. The Aegis web site, updated hourly, is an excellent starting point for obtaining detailed information about HIV and the dementia that sometimes accompanies it. Following their links will lead you to more sources than you probably have time to read. Last updated 12/19/03 |
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