Healthinmind/Mental
Health Disorders/Sleep DisordersNarcolepsy
Narcolepsy can be regarded as an extreme
form of Hypersomnia.
However, it is not certain that the two disorders are versions of
the same underlying disorder, although some people with
Hypersomnia behave much like people with mild Narcolepsy.
In Narcolepsy, the person has irresistible
episodes of sleep over a period of at least 3 months. In addition,
victims usually have either cataplexy (sudden loss of muscle tone)
or hallucinatory experiences at the beginning or end of sleep
attacks.
Again, all the usual suspects must be excluded,
and the disorder must cause significant distress or impairment (an
easy criterion to fulfill in the case of Narcolepsy; but,
amazingly, most victims don't seek help until years after the
onset).
Some patients are helped by treatment with
stimulants, but many symptoms of Narcolepsy are likely to be
chronic. The disorder seldom appears before adolescence or after
age 40, although there are exceptions. There appear to
be genetic factors in Narcolepsy, as well as in other associated
mental disorders; depression and anxiety, understandably, are
among the most common ones.
On August 31, 2000, the San Francisco Chronicle
reported that researchers at Stanford University and at the
University of California at Los Angeles, publishing in the
journal, Neuron, discovered that most of the cells that
produce a hormone called hypocretin (also called orexin) were dead
in the brains of people with narcolepsy. The hormone was already
known to have a role in sleep regulation; hence, this knowledge
may lead to better drug treatments for narcolepsy.
The Narcolepsy
Network can be reached for further information.
Last updated 12/19/03
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